SCHEMBL8414130

SCHEMBL8414130

C[Si](C)(C)c1cccc(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 4/20 0.52
CA12 O43570 3/20 0.52
CA2 P00918 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 2/20 0.52
LMNA P02545 1/20 0.52
CA5A P35218 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ACHE P22303 3/20 0.48
HSD17B1 P14061 5/20 0.43
HSD17B2 P37059 4/20 0.43
TSHR P16473 2/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
CA1 P00915 2/20 0.42
CYP2C9 P11712 1/20 0.42
CA7 P43166 1/20 0.42
TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30209191 1.00 ALDH1A1 (0.52) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL10340797 0.85 ESR1 (0.54) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL14163942 0.81 ALDH1A1 (0.48) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL30947417 0.81 ESR1 (0.50) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL4572715 0.81 ACHE (0.48) ACHEESR1ESR2
SCHEMBL14163941 0.79 ESR1 (0.48) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL10338155 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL10950622 0.79 ESR1 (0.65) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL2548283 0.79 CA12 (0.58) ALDH1A1CYP3A4CA12CA2CA9
SCHEMBL79324 0.78 ALDH1A1 (0.44) ALDH1A1CYP3A4CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115863766-B Nonaqueous electrolyte and lithium ion battery 如鲲(江苏)新材料科技有限公司 2023-05-16 CN disclosed
CN-115863766-A Non-aqueous electrolyte and lithium ion battery 如鲲(江苏)新材料科技有限公司 2023-03-28 CN disclosed
US-8895688-B2 Halogen-free flame retarding materials based on bisphenol triazole resins and polymers UNIVERSITY OF MASSCHUSETTS (US) 2014-11-25 US disclosed
US-20120316313-A1 HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS UNIVERSITY OF MASSACHUSETTS 2012-12-13 US disclosed
EP-0601642-B1 Photographic silver halide material and process EASTMAN KODAK CO (US) 1999-09-01 EP disclosed
EP-0601642-A1 Photographic silver halide material and process EASTMAN KODAK COMPANY (US) 1994-06-15 EP disclosed
US-5306604-A Dispersibility, low melting points EASTMAN KODAK COMPANY (US) 1994-04-26 US disclosed
EP-0185030-B1 BILEVEL RESIST AT&T Corp. (US) 1988-11-02 EP disclosed
EP-0185030-A1 AMERICAN TELEPHONE & TELEGRAPH 1986-06-25 EP disclosed
WO-1985005470-A1 BILEVEL RESIST AMERICAN TELEPHONE & TELEGRAPH COMPANY (US) 1985-12-05 WO disclosed
US-4521274-A Bilevel resist AT&T BELL LABORATORIES (US) 1985-06-04 US disclosed
EP-0040741-B1 PROCESS FOR THE PREPARATION OF CHLOROFORMIC-ACID ARYL ESTERS BAYER AG (DE) 1983-06-08 EP disclosed
US-4366102-A Process for the preparation of chloroformic acid aryl esters BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0040741-A1 Process for the preparation of chloroformic-acid aryl esters BAYER AG (DE) 1981-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316313-A1 HALOGEN-FREE FLAME RETARDING MATERIALS BASED ON BISPHENOL TRIAZOLE RESINS AND POLYMERS FFAR3, FHIT, BRPF3 ALDH1A1 2139/4885CYP3A4 98/4885CA12 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.