Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411821 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL7411462 | 0.87 | F10 (0.57) | KMT2APKMMEN1POLBABCB1 | |
| SCHEMBL7407435 | 0.87 | F10 (0.57) | KMT2APKMMEN1POLBABCB1 | |
| SCHEMBL8414778 | 0.85 | PDE4D (0.67) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL7413404 | 0.82 | KMT2A (0.64) | ALDH1A1KMT2APKMMEN1PDE4D | |
| SCHEMBL8417461 | 0.82 | KMT2A (0.64) | ALDH1A1KMT2APKMMEN1PDE4D | |
| SCHEMBL7411534 | 0.80 | POLB (0.65) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL7408481 | 0.80 | POLB (0.65) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL8417467 | 0.78 | KMT2A (0.53) | ALDH1A1KMT2APKMMEN1LMNA | |
| SCHEMBL8414166 | 0.78 | CHEK1 (0.51) | ALDH1A1KMT2APKMMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |