Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574993 | 0.73 | CYP11B1 (0.42) | ELANEUSP14CYP11B1CYP11B2PARP1 | |
| SCHEMBL8414876 | 0.68 | GRM2 (0.35) | ELANE | |
| SCHEMBL8575545 | 0.68 | P2RX3 (0.34) | — | |
| SCHEMBL8575389 | 0.65 | GAA (0.35) | PARP1 | |
| SCHEMBL8577361 | 0.63 | CYP4F2 (0.37) | — | |
| SCHEMBL8575775 | 0.63 | PPARD (0.40) | — | |
| SCHEMBL8576047 | 0.63 | HRH3 (0.38) | — | |
| SCHEMBL8413731 | 0.63 | TDP1 (0.36) | — | |
| SCHEMBL8417173 | 0.61 | HTT (0.45) | ELANE | |
| SCHEMBL8575282 | 0.60 | TDP1 (0.36) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |