Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572785 | 0.87 | NSD2 (0.37) | TSHRLMNARAB9ASMN1; SMN2GAA | |
| SCHEMBL8577364 | 0.84 | CYP4F2 (0.42) | CYP4F2CYP4A11CTSGCMA1LMNA | |
| Hydrochloric Acid SCHEMBL8571560 | 0.77 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8575545 | 0.77 | P2RX3 (0.34) | CYP4F2CYP4A11TSHRLMNARAB9A | |
| SCHEMBL8574007 | 0.76 | ITGB3 (0.39) | — | |
| SCHEMBL8575777 | 0.73 | QPCT (0.43) | ALDH1A1MAPTFAAHKCNH2 | |
| Hydrochloric Acid SCHEMBL8577444 | 0.73 | SIRT2 (0.36) | GCK | |
| SCHEMBL8575282 | 0.68 | TDP1 (0.36) | CYP4F2CYP4A11TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8577440 | 0.67 | HRH3 (0.35) | GCKKCNH2 | |
| SCHEMBL8735781 | 0.67 | CYP4F2 (0.70) | CYP4F2CYP4A11TSHRLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |