Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571705 | 0.89 | PPARD (0.41) | PPARDMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8577361 | 0.87 | CYP4F2 (0.37) | FAAHMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8575777 | 0.83 | QPCT (0.43) | FAAHMAPTALDH1A1KDM4EQPCT | |
| SCHEMBL8572785 | 0.79 | NSD2 (0.37) | SMN1; SMN2QPCTTSHRRAB9APOLB | |
| SCHEMBL8575545 | 0.74 | P2RX3 (0.34) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8577364 | 0.74 | CYP4F2 (0.42) | MAPTSMN1; SMN2ALDH1A1QPCTQPCTL | |
| SCHEMBL8571709 | 0.73 | PPARD (0.45) | PPARDQPCTQPCTL | |
| SCHEMBL8574007 | 0.72 | ITGB3 (0.39) | QPCTQPCTL | |
| SCHEMBL8575389 | 0.71 | GAA (0.35) | MAPTALDH1A1KDM4EHPGDQPCT | |
| SCHEMBL8572954 | 0.67 | NOS3 (0.39) | MAPTALDH1A1KDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |