Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117175 | 0.81 | GABRA1 (0.46) | EGLN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL9318876 | 0.80 | EGLN1 (0.47) | EGLN1CYP1A2CYP2A6GABRA1GABRG2 | |
| SCHEMBL29840564 | 0.79 | LCK (0.56) | EGLN1CYP1A2CYP2A6GABRA1GABRG2 | |
| SCHEMBL214090 | 0.79 | LCK (0.56) | EGLN1CYP1A2CYP2A6GABRA1GABRG2 | |
| SCHEMBL5889663 | 0.78 | TDP1 (0.41) | MEN1KMT2ATDP1NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27800514 | 0.78 | LCK (0.55) | EGLN1CYP1A2CYP2A6GABRA1GABRG2 | |
| SCHEMBL5805411 | 0.77 | MAPT (0.57) | MEN1KMT2ATDP1GABRA1GABRG2 | |
| SCHEMBL27950633 | 0.76 | EGLN1 (0.43) | EGLN1CYP1A2CYP2A6GABRA1GABRG2 | |
| SCHEMBL7025748 | 0.75 | GABRG2 (0.57) | EGLN1CYP1A2CYP2A6GABRA1GABRG2 | |
| SCHEMBL3834448 | 0.75 | KDM4E (0.48) | EGLN1MEN1KMT2ACYP1A2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972927-A | ANTIINFLAMMATORY, ANTIALLERGIC AND BRONCHODILATORY MEDICINAL PRODUCTS, TREATMENT OF ASTHMA | JOUVEINAL (FR) | 1999-10-26 | — | — | US | disclosed |