SCHEMBL8415076

SCHEMBL8415076

NC(=O)CCCC(=O)NCCCCCS

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 10/20 0.46
HDAC1 Q13547 10/20 0.46
HDAC2 Q92769 10/20 0.46
HDAC10 Q969S8 10/20 0.46
HDAC11 Q96DB2 10/20 0.46
HDAC8 Q9BY41 10/20 0.46
HDAC6 Q9UBN7 10/20 0.46
HDAC4 P56524 8/20 0.46
HDAC7 Q8WUI4 8/20 0.46
HDAC9 Q9UKV0 8/20 0.46
HDAC5 Q9UQL6 8/20 0.46
CASP2 P42575 1/20 0.46
TSHR P16473 1/20 0.44
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NAAA Q02083 1/20 0.43
DNM1 Q05193 2/20 0.42
SLC6A5 Q9Y345 2/20 0.41
FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8415080 0.92 CASP2 (0.46) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL8414996 0.92 TSHR (0.47) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL8411516 0.86 HDAC3 (0.54) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL1940161 0.86 CASP2 (0.54) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL4633503 0.86 HDAC3 (0.49) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL9128874 0.85 SLC6A5 (0.51) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL8413284 0.84 HDAC3 (0.40) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL8413444 0.84 ALDH1A1 (0.46) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL15076046 0.83 SLC6A5 (0.58) HDAC3HDAC1HDAC2HDAC10HDAC11
SCHEMBL15452325 0.83 SLC6A5 (0.58) HDAC3HDAC1HDAC2HDAC10HDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985257-A HAIR PERMANENT L'OREAL (FR) 1999-11-16 US claimed
US-5935558-A FOR PERMANENT WAVING OF HAIR; IMPROVED CURLING, LOW ODOR L'OREAL, SA (FR) 1999-08-10 US claimed
EP-0653202-B1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent OREAL (FR) 1998-03-04 EP claimed
EP-0653202-A1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent L'OREAL (FR) 1995-05-17 EP claimed
US-5985257-A HAIR PERMANENT L'OREAL (FR) 1999-11-16 US disclosed
US-5935558-A FOR PERMANENT WAVING OF HAIR; IMPROVED CURLING, LOW ODOR L'OREAL, SA (FR) 1999-08-10 US disclosed
US-5843416-A Cosmetic composition containing an n-mercaptoalkylalkanediamide or one of its cosmetically acceptable salts as reducing agent L'OREAL (FR) 1998-12-01 US disclosed
EP-0653202-B1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent OREAL (FR) 1998-03-04 EP disclosed
US-5700454-A FOR PERMANENT WAVING OF HAIR WITH IMPROVED CURLING EFFICIENCY L'OREAL (FR) 1997-12-23 US disclosed
EP-0653202-A1 Cosmetic composition containing an N-mercaptoalkyl alkanediamide or one of its cosmetically acceptable salts as a reducing agent L'OREAL (FR) 1995-05-17 EP disclosed