Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MMP8 | P22894 | 11/20 | 0.44 |
| ▸ | MMP9 | P14780 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 10/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286461 | 0.77 | LMNA (0.36) | LMNA | |
| SCHEMBL472546 | 0.75 | LMNA (0.44) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| SCHEMBL17294138 | 0.75 | LMNA (0.50) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL3859278 | 0.74 | LMNA (1.00) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL43818 | 0.74 | LMNA (1.00) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL23533431 | 0.72 | LMNA (0.94) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL236590 | 0.72 | LMNA (0.94) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL21084914 | 0.72 | LMNA (0.94) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL21084955 | 0.72 | LMNA (0.94) | LMNAMMP8MMP9ALDH1A1KDM4E | |
| Barbital SCHEMBL11332231 | 0.72 | LMNA (0.94) | LMNAMMP8MMP9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565074-B1 | Process for the preparation of binary sensitizing dyes | EASTMAN KODAK CO (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0565074-A2 | Process for the preparation of binary sensitizing dyes | EASTMAN KODAK COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |