SCHEMBL472546

SCHEMBL472546

CCCCC1(O)C(=O)NC(=O)NC1=O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
MMP9 P14780 8/20 0.43
MMP2 P08253 7/20 0.43
MMP3 P08254 2/20 0.43
MMP13 P45452 6/20 0.42
MMP8 P22894 6/20 0.42
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
GABRB3 P28472 1/20 0.38
OPRD1 P41143 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17294163 0.79 MMP2 (0.39) LMNAMMP9MMP2MMP3MMP13
SCHEMBL1683293 0.79 LMNA (0.58) LMNAMMP9MMP2MMP3MMP13
SCHEMBL2850139 0.77 MMP2 (0.45) LMNAMMP9MMP2MMP3MMP13
SCHEMBL11256550 0.76 MMP13 (0.43) LMNAMMP9MMP2MMP3MMP13
Butethal SCHEMBL44262 0.76 LMNA (0.67) LMNAMMP9MMP2MMP3MMP13
SCHEMBL5272059 0.76 LMNA (0.43) LMNAMMP9MMP2MMP3MMP13
SCHEMBL11273946 0.76 MMP13 (0.43) LMNAMMP9MMP2MMP3MMP13
SCHEMBL8415310 0.75 LMNA (0.59) LMNAMMP9MMP2MMP3MMP8
SCHEMBL11109611 0.75 MMP9 (0.49) LMNAMMP9MMP2MMP3MMP13
Butethal SCHEMBL2718536 0.74 LMNA (0.64) LMNAMMP9MMP2MMP3MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO claimed
EP-1387659-B1 INITIATOR SYSTEM FOR ACID DENTAL FORMULATIONS 3M ESPE AG (DE) 2008-05-07 EP claimed
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US disclosed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP disclosed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO disclosed
US-9937106-B2 Kit of parts, method of producing and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-04-10 US disclosed
US-20170056299-A1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2017-03-02 US disclosed
EP-2598101-B1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2017-01-25 EP disclosed
US-9498313-B2 Kit of parts, method of producing and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-11-22 US disclosed
US-9144626-B2 Paste for producing bone cement HERAEUS MEDICAL GMBH (DE) 2015-09-29 US disclosed
US-8791172-B2 Three-component bone cement HERAEUS MEDICAL GMBH (DE) 2014-07-29 US disclosed
US-20130143176-A1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-06 US disclosed
EP-2598101-A1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF 3M Innovative Properties Company (US) 2013-06-05 EP disclosed
WO-2012015814-A1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-02-02 WO disclosed
EP-2412361-A1 Kit of parts, method of producing and use thereof 3M Innovative Properties Company (US) 2012-02-01 EP disclosed
US-20110183932-A1 THREE-COMPONENT BONE CEMENT HERAEUS MEDICAL GMBH (DE) 2011-07-28 US disclosed
US-6953535-B2 Initiator system for acid dental formulations 3M ESPE AG (DE) 2005-10-11 US disclosed
US-20040097613-A1 Initiator system for acid dental formulations 3M INNOVATIVE PROPERTIES COMPANY 2004-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170056299-A1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF KIT, C9, F13B LMNA 625/4885MMP9 583/4885MMP2 510/4885
US-20130143176-A1 KIT OF PARTS, METHOD OF PRODUCING AND USE THEREOF KIT, C9, F13B LMNA 540/4885MMP9 754/4885MMP2 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.