Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | GFER | P55789 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264045 | 0.77 | OPRM1 (0.42) | KMT2ATDP1OPRK1 | |
| SCHEMBL21247952 | 0.77 | OPRM1 (0.38) | MAPTKMT2AMEN1PNMTRAD52 | |
| SCHEMBL5886235 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNAL3MBTL1NSD2MAPT | |
| SCHEMBL22918208 | 0.71 | HPGD (0.39) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL4762433 | 0.71 | MAPT (0.43) | ALDH1A1LMNAMAPTGFERKMT2A | |
| SCHEMBL22996217 | 0.71 | OPRM1 (0.34) | MAPTKMT2AMEN1NPSR1RAD52 | |
| SCHEMBL22996210 | 0.71 | SIGMAR1 (0.39) | KMT2AOPRK1 | |
| SCHEMBL1431010 | 0.70 | PEPD (0.47) | ALDH1A1LMNAMAPTGFERKMT2A | |
| SCHEMBL15354900 | 0.70 | ALDH1A1 (0.53) | ALDH1A1LMNAL3MBTL1NSD2MAPT | |
| SCHEMBL4227685 | 0.67 | LTA4H (0.40) | PNMTSMN1; SMN2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |