Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242342 | 0.86 | KMT2A (0.56) | LMNAKMT2ACYP3A4ALDH1A1KDM4E | |
| SCHEMBL6905593 | 0.84 | LMNA (0.48) | LMNAKMT2ACYP3A4ALDH1A1KDM4E | |
| SCHEMBL6907787 | 0.84 | LMNA (0.48) | LMNAKMT2ACYP3A4ALDH1A1KDM4E | |
| SCHEMBL6909985 | 0.83 | LMNA (0.47) | LMNACYP3A4ALDH1A1KDM4EACHE | |
| SCHEMBL8415298 | 0.81 | ALDH1A1 (0.63) | LMNACYP3A4ALDH1A1KDM4ETHRB | |
| SCHEMBL16318959 | 0.80 | TSPO (0.49) | LMNAKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL14156361 | 0.80 | SMN1; SMN2 (0.47) | LMNACYP3A4ALDH1A1KDM4ETHRB | |
| SCHEMBL6486619 | 0.78 | SMN1; SMN2 (0.54) | KMT2AALDH1A1MEN1PPARGSMN1; SMN2 | |
| SCHEMBL7595655 | 0.78 | KMT2A (0.45) | LMNAKMT2ACYP3A4ALDH1A1KDM4E | |
| SCHEMBL9059920 | 0.77 | CYP3A4 (0.51) | LMNAKMT2ACYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565074-B1 | Process for the preparation of binary sensitizing dyes | EASTMAN KODAK CO (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5756740-A | Process for the preparation of binary sensitizing dyes | EASTMAN KODAK COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0565074-A2 | Process for the preparation of binary sensitizing dyes | EASTMAN KODAK COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |