SCHEMBL9435949

SCHEMBL9435949

Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccc(Sc2ccc(NC(=O)NS(=O)(=O)c3ccccc3C)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.62
CA9 Q16790 8/20 0.62
CA2 P00918 7/20 0.62
CA12 O43570 6/20 0.62
FBP1 P09467 1/20 0.51
LMNA P02545 1/20 0.49
MMP1 P03956 2/20 0.48
MMP2 P08253 2/20 0.48
MMP9 P14780 2/20 0.48
MMP8 P22894 2/20 0.48
MMP13 P45452 2/20 0.48
POLB P06746 1/20 0.45
KCNJ6 P48051 1/20 0.44
KCNJ5 P48544 1/20 0.44
KCNJ3 P48549 1/20 0.44
TP53 P04637 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2303216 0.87 LMNA (0.63) CA1CA9CA2CA12FBP1
SCHEMBL9487024 0.84 CA12 (0.60) CA1CA9CA2CA12FBP1
SCHEMBL8415189 0.84 CA1 (0.62) CA1CA9CA2CA12FBP1
SCHEMBL7774865 0.83 CA1 (0.59) CA1CA9CA2CA12FBP1
SCHEMBL6331212 0.82 CA1 (0.61) CA1CA9CA2CA12FBP1
SCHEMBL8416340 0.82 CA9 (0.63) CA1CA9CA2CA12FBP1
SCHEMBL8416302 0.80 CA12 (0.61) CA1CA9CA2CA12FBP1
SCHEMBL8726381 0.79 FBP1 (0.58) CA1CA9CA2CA12FBP1
SCHEMBL5528983 0.77 CA12 (0.72) CA1CA9CA2CA12LMNA
SCHEMBL6326396 0.76 CA1 (0.52) CA1CA9CA2CA12FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6345720-A None JP disclosed
JP-H06345720-A NEW 4,4'-BIS(O-TOLUENESULFONYLAMINOCARBONYLAMINO) DIPHENYL COMPOUND NEW OJI PAPER CO LTD 1994-12-20 JP disclosed