SCHEMBL8726381

SCHEMBL8726381

Cc1ccccc1S(=O)(=O)NC(=O)Nc1ccccc1NC(=O)NS(=O)(=O)c1ccccc1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.58
CA1 P00915 5/20 0.56
CA2 P00918 5/20 0.56
CA9 Q16790 5/20 0.56
CA12 O43570 3/20 0.56
ALDH1A1 P00352 1/20 0.52
RECQL P46063 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
POLB P06746 2/20 0.50
KMT2A Q03164 1/20 0.48
GAA P10253 1/20 0.46
NLRP3 Q96P20 1/20 0.46
ALKBH2 Q6NS38 1/20 0.46
ALKBH3 Q96Q83 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8417081 0.91 NLRP3 (0.54) FBP1CA1CA2CA9CA12
SCHEMBL8415196 0.89 FBP1 (0.54) FBP1CA1CA2CA9CA12
SCHEMBL8415189 0.85 CA1 (0.62) FBP1CA1CA2CA9CA12
SCHEMBL2303216 0.85 LMNA (0.63) FBP1CA1CA2CA9CA12
SCHEMBL8416302 0.84 CA12 (0.61) FBP1CA1CA2CA9CA12
SCHEMBL6882367 0.82 CA1 (0.50) FBP1CA1CA2CA9CA12
SCHEMBL29489589 0.81 CA1 (0.55) FBP1CA1CA2CA9CA12
SCHEMBL6465947 0.81 CA1 (0.55) FBP1CA1CA2CA9CA12
SCHEMBL6322119 0.81 L3MBTL1 (0.59) FBP1CA1CA2CA9CA12
SCHEMBL3206422 0.80 SLC1A3 (0.55) FBP1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10044619-A None JP disclosed
JP-H1044619-A NEW DEVELOPER COMPOSED OF BIS(P-TOLUENESULFONYLAMINO CARBONYLAMINO)-BENZENE DERIVATIVE KEMIPURO KASEI KK 1998-02-17 JP disclosed