SCHEMBL841684

SCHEMBL841684

COC(=O)c1cc(O)cc(C(=O)O)c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.52
CA1 P00915 5/20 0.52
CA2 P00918 5/20 0.52
CA7 P43166 5/20 0.52
CA9 Q16790 5/20 0.52
CA14 Q9ULX7 5/20 0.52
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47
POLB P06746 3/20 0.46
MAPT P10636 3/20 0.46
RECQL P46063 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP3A4 P08684 2/20 0.46
ACHE P22303 1/20 0.46
NPC1 O15118 1/20 0.46
ABL1 P00519 1/20 0.46
PKM P14618 1/20 0.46
BLM P54132 1/20 0.46
BCL2L1 Q07817 1/20 0.46
MCL1 Q07820 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27138531 0.86 KDM4E (0.46) CA12CA1CA2CA7CA9
SCHEMBL25669658 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL15009548 0.85 TPMT (0.43) CA12CA1CA2CA7CA9
SCHEMBL2226012 0.83 HSD17B10 (0.51) CA12CA1CA2CA7CA9
SCHEMBL5226978 0.83 POLB (0.50) CA1CA2POLBMAPTKDM4E
SCHEMBL1271994 0.83 KDM4E (0.61) POLBMAPTRECQLKDM4ECYP3A4
SCHEMBL5262901 0.83 KDM4E (0.39) CA12CA1CA2CA7CA9
SCHEMBL2318334 0.82 CYP3A4 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2650424 0.82 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL12112823 0.81 CA12 (0.52) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2788366-B1 PREPARATION OF (PHOSPHONYL) AROMATIC DIESTERS AND ACIDS DU PONT (US) 2018-01-24 EP claimed
EP-2788366-A1 PREPARATION OF (PHOSPHONYL) AROMATIC DIESTERS AND ACIDS E. I. Du Pont de Nemours and Company (US) 2014-10-15 EP claimed
WO-2013085620-A1 PREPARATION OF (PHOSPHONYL) AROMATIC DIESTERS AND ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-13 WO claimed
US-20130150612-A1 PREPARATION OF (PHOSPHONYL) AROMATIC DIESTERS AND ACIDS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2013-06-13 US claimed
EP-3635022-B1 METHODS FOR MAKING FUNCTIONALIZED FLUORINATED MONOMERS, FLUORINATED MONOMERS, AND COMPOSITIONS FOR MAKING THE SAME ETNA TEC LTD (US) 2025-05-21 EP disclosed
US-20240352208-A1 A Membrane and a Method of Making the Same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2024-10-24 US disclosed
US-11820840-B2 Compound, polymer, pattern forming material, and manufacturing method of semiconductor device KIOXIA CORPORATION (JP) 2023-11-21 US disclosed
US-20230220130-A1 COMPOUND, POLYMER, PATTERN FORMING MATERIAL, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE KIOXIA CORPORATION (JP) 2023-07-13 US disclosed
US-11639402-B2 Polymer for pattern forming material KIOXIA CORPORATION (JP) 2023-05-02 US disclosed
US-20230117826-A1 COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME MOLECULAR TARGETING TECHNOLOGIES, INC. 2023-04-20 US disclosed
WO-2023033723-A2 A MEMBRANE AND A METHOD OF MAKING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-03-09 WO disclosed
US-11492318-B2 Methods for making functionalized fluorinated monomers, fluorinated monomers, and compositions for making the same ETNA-TEC, LTD. (US) 2022-11-08 US disclosed
EP-1095071-A1 AROMATIC POLYMERS WITH PENDANT FLUORINATED IONIC GROUPS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2001-05-02 EP disclosed
WO-1999067304-A1 AROMATIC POLYMERS WITH PENDANT FLUORINATED IONIC GROUPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-12-29 WO disclosed
EP-0954531-A1 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES Lajolla Pharmaceutical Company (US) 1999-11-10 EP disclosed
EP-0954531-A4 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES LAJOLLA PHARMACEUTICAL COMPANY (US) 1999-08-31 EP disclosed
EP-0684963-B1 WATER-DISSIPATABLE POLYESTERS AND AMIDES CONTAINING NEAR INFRARED FLUORESCENT COMPOUNDS COPOLYMERIZED THEREIN EASTMAN CHEM CO (US) 1998-07-29 EP disclosed
WO-1997046251-A9 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES 1998-06-04 WO disclosed
WO-1997046251-A1 aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES LAJOLLA PHARMACEUTICAL COMPANY (US) 1997-12-11 WO disclosed
US-5616659-A Low flammability thermoset polymers SOUTHWEST RESEARCH INSTITUTE (US) 1997-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820840-B2 Compound, polymer, pattern forming material, and manufacturing method of semiconductor device C9, H1-2, H1-3 CA12 203/4885CA1 1124/4885CA2 3431/4885
US-20130150612-A1 PREPARATION OF (PHOSPHONYL) AROMATIC DIESTERS AND ACIDS HRH3, PNN, H1-0 CA12 2867/4885CA1 1786/4885CA2 1356/4885
US-11492318-B2 Methods for making functionalized fluorinated monomers, fluorinated monomers, and compositions for making the same ALKBH3, FTO, ALK CA12 1388/4885CA1 919/4885CA2 2671/4885
US-20230117826-A1 COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME ALDH1A2, PDE6C, ALDH1A3 CA12 2196/4885CA1 3362/4885CA2 1032/4885
US-11639402-B2 Polymer for pattern forming material PUF60, METTL14, MECP2 CA12 3127/4885CA1 4006/4885CA2 4840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.