Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 4/20 | 0.32 |
| ▸ | IL1RN | P18510 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413437 | 0.94 | OPRD1 (0.40) | PTGER3PTGER2OPRD1 | |
| SCHEMBL8417042 | 0.91 | CTSG (0.35) | PTGER2F10OPRD1MTNR1A | |
| Hydrochloric Acid SCHEMBL8571507 | 0.90 | CTSG (0.34) | PTGER2F10OPRD1MTNR1A | |
| SCHEMBL8415372 | 0.85 | OPRD1 (0.39) | OPRD1 | |
| Hydrochloric Acid SCHEMBL8576436 | 0.84 | OPRD1 (0.39) | OPRD1 | |
| SCHEMBL8575501 | 0.79 | PTGER3 (0.35) | PTGER3PTGER2FFAR4PPARD | |
| SCHEMBL8573785 | 0.76 | FFAR4 (0.39) | PTGER3PTGER2OPRD1FFAR4FFAR1 | |
| SCHEMBL7283416 | 0.73 | S1PR1 (0.42) | F10OPRD1FFAR4PPARDFFAR1 | |
| Hydrochloric Acid SCHEMBL8573565 | 0.71 | CTSG (0.39) | — | |
| SCHEMBL8575472 | 0.70 | PTGER3 (0.38) | PTGER3PTGER2F10FFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |