Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415391 | 0.89 | NPC1 (0.38) | KDM4EALDH1A1LMNACHRM1 | |
| SCHEMBL8413812 | 0.88 | KDM4E (0.39) | ITGB3ITGA2BITGA2KDM4EALDH1A1 | |
| SCHEMBL8417066 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BITGA2 | |
| SCHEMBL8575558 | 0.79 | LMNA (0.37) | KDM4EALDH1A1LMNA | |
| SCHEMBL8575282 | 0.72 | TDP1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL3815926 | 0.71 | SLC18A3 (0.44) | — | |
| SCHEMBL4610243 | 0.71 | SLC18A3 (0.44) | — | |
| Hydrochloric Acid SCHEMBL4049067 | 0.70 | KDM1A (0.40) | — | |
| SCHEMBL8413814 | 0.69 | HRH3 (0.46) | ITGB3ITGA2BITGA2 | |
| Hydrochloric Acid SCHEMBL8415510 | 0.68 | FFAR4 (0.40) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |