Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414030 | 0.83 | ALDH1A1 (0.37) | KMT2AALDH1A1HPGDATMPTGS1 | |
| SCHEMBL8417205 | 0.81 | ERCC1 (0.37) | KMT2AALDH1A1ATMPTGS1PTGS2 | |
| SCHEMBL31612953 | 0.64 | KMT2A (0.50) | KMT2AALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL8676087 | 0.64 | KMT2A (0.50) | KMT2AALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL8472060 | 0.64 | KMT2A (0.50) | KMT2AALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL6240135 | 0.63 | KMT2A (0.47) | KMT2AALDH1A1HTTHPGDPTGS1 | |
| SCHEMBL6017451 | 0.63 | KMT2A (0.47) | KMT2AALDH1A1HTTPTGS1PTGS2 | |
| SCHEMBL11321177 | 0.63 | PTGS1 (0.34) | KMT2AALDH1A1HTTHPGDPTGS1 | |
| SCHEMBL31517035 | 0.62 | GABRA1 (0.52) | KMT2AALDH1A1PTGS1PTGS2MEN1 | |
| SCHEMBL1345444 | 0.62 | GABRA1 (0.52) | KMT2AALDH1A1PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |