Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417205 | 0.84 | ERCC1 (0.37) | ALDH1A1KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL8417128 | 0.83 | KMT2A (0.35) | ALDH1A1KMT2AHPGDMEN1PTGS1 | |
| SCHEMBL9052724 | 0.75 | KMT2A (0.43) | ALDH1A1KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL6017451 | 0.70 | KMT2A (0.47) | ALDH1A1KMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL9119609 | 0.69 | CDK4 (0.50) | ALDH1A1SMN1; SMN2PKMKDM4ELMNA | |
| SCHEMBL4160190 | 0.67 | KMT2A (0.44) | ALDH1A1KMT2AHPGDMEN1PTGS1 | |
| SCHEMBL20921259 | 0.67 | KMT2A (0.44) | ALDH1A1KMT2AHPGDMEN1PTGS1 | |
| SCHEMBL6240135 | 0.66 | KMT2A (0.47) | ALDH1A1KMT2AHPGDMEN1PTGS1 | |
| SCHEMBL8386511 | 0.66 | HCAR1 (0.47) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL11321177 | 0.66 | PTGS1 (0.34) | ALDH1A1KMT2AHPGDMEN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |