Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414030 | 0.84 | ALDH1A1 (0.37) | ATMADORA3KDM4ESMN1; SMN2PTGS1 | |
| SCHEMBL8417128 | 0.81 | KMT2A (0.35) | ATMKDM4EPTGS1PTGS2LMNA | |
| SCHEMBL7652867 | 0.76 | ALDH1A1 (0.48) | TNKSKDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL7657329 | 0.75 | ADORA3 (0.54) | ATMTNKSADORA3ADORA1KDM4E | |
| SCHEMBL7654102 | 0.72 | ADORA2B (0.41) | TNKSADORA3ADORA1KDM4ELMNA | |
| SCHEMBL10710439 | 0.71 | KMT2A (0.46) | KDM4EPTGS1PTGS2LMNAKMT2A | |
| SCHEMBL7652334 | 0.70 | HCAR1 (0.39) | ATMTNKSADORA3NPC1ADORA2A | |
| SCHEMBL7650490 | 0.70 | MAPK11 (0.40) | TNKSADORA3KDM4EALDH1A1 | |
| SCHEMBL7654345 | 0.70 | GAA (0.40) | TNKSADORA3KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7649183 | 0.69 | CDK4 (0.43) | TNKSADORA3TP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |