Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417505 | 0.93 | ALDH1A1 (0.46) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL8417532 | 0.91 | SIGMAR1 (0.40) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL8419454 | 0.91 | UTS2R (0.44) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8419633 | 0.90 | SIGMAR1 (0.39) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL8421571 | 0.89 | UTS2R (0.42) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8419845 | 0.89 | SIGMAR1 (0.40) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL8421357 | 0.88 | MMP2 (0.38) | ALDH1A1MMP2MMP9MMP13LMNA | |
| SCHEMBL8419271 | 0.88 | UTS2R (0.43) | ALDH1A1KMT2AMEN1HDAC1 | |
| SCHEMBL8895359 | 0.87 | HSD17B10 (0.49) | ALDH1A1POLBMMP2MMP9MMP8 | |
| SCHEMBL8418072 | 0.86 | SIGMAR1 (0.39) | ALDH1A1POLBMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |