Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419633 | 0.98 | SIGMAR1 (0.39) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8419845 | 0.97 | SIGMAR1 (0.40) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8418072 | 0.94 | SIGMAR1 (0.39) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8417445 | 0.93 | SIGMAR1 (0.40) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8419595 | 0.93 | FFAR1 (0.39) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8417431 | 0.92 | EEF2K (0.37) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8419454 | 0.91 | UTS2R (0.44) | EEF2KALDH1A1NPSR1IDO1CYP1A2 | |
| SCHEMBL8417302 | 0.91 | ALDH1A1 (0.46) | RAB9AALDH1A1POLBMMP2MMP9 | |
| SCHEMBL8419365 | 0.91 | SIGMAR1 (0.40) | SIGMAR1EEF2KFFAR1FFAR4RAB9A | |
| SCHEMBL8896082 | 0.91 | SIGMAR1 (0.41) | SIGMAR1EEF2KFFAR1FFAR4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943606-A1 | BENZENESULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-22 | — | — | EP | disclosed |