Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417421 | 0.93 | AGTR1 (0.34) | — | |
| SCHEMBL8417914 | 0.89 | PDCD1 (0.36) | — | |
| SCHEMBL8419603 | 0.89 | AGTR1 (0.34) | — | |
| SCHEMBL8419023 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL8631046 | 0.89 | PLA2G2A (0.33) | PLA2G2A | |
| SCHEMBL8421091 | 0.88 | BDKRB1 (0.34) | — | |
| SCHEMBL8418010 | 0.88 | POLB (0.33) | — | |
| SCHEMBL8417423 | 0.87 | RIPK1 (0.36) | — | |
| SCHEMBL8417952 | 0.85 | AGTR1 (0.34) | — | |
| SCHEMBL8419127 | 0.85 | AGTR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962491-A | ANGIOTENSIN ANTAGONIST, HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5763619-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS OR STROKES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| US-5703110-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-30 | — | — | US | disclosed |