Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417473 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2PDE4B | |
| SCHEMBL6598031 | 0.82 | F2 (0.57) | F2PRSS1MEN1KMT2ANPSR1 | |
| SCHEMBL1902995 | 0.81 | HRH1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2SCD | |
| SCHEMBL8419487 | 0.81 | SMN1; SMN2 (0.58) | MEN1KMT2ANPSR1SMN1; SMN2PDE4B | |
| SCHEMBL8419333 | 0.77 | GAA (0.57) | MEN1KMT2ANPSR1ALDH1A1TSHR | |
| SCHEMBL2636818 | 0.77 | SCD (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2SCD | |
| SCHEMBL1901129 | 0.77 | HRH1 (0.44) | MEN1KMT2AALDH1A1SMN1; SMN2SCD | |
| SCHEMBL24590680 | 0.77 | TEAD3 (0.47) | KMT2ASCDHDAC1HDAC2 | |
| SCHEMBL24590454 | 0.77 | NAMPT (0.47) | MEN1KMT2AALDH1A1SCD | |
| SCHEMBL8327398 | 0.76 | L3MBTL1 (0.49) | MEN1KMT2AALDH1A1TSHRPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889025-A | Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-30 | — | — | US | disclosed |