Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417706 | 0.69 | SLC6A4 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20876291 | 0.67 | CYP2D6 (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL22130964 | 0.67 | CFTR (0.41) | — | |
| SCHEMBL25094761 | 0.67 | HDAC4 (0.41) | ALOX15ALOX12SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1426726 | 0.66 | SLC6A4 (0.40) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8520386 | 0.66 | RXRA (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20558236 | 0.64 | CYP19A1 (0.33) | SLC6A4SLC6A3 | |
| SCHEMBL25094707 | 0.64 | HDAC4 (0.39) | — | |
| SCHEMBL25093296 | 0.64 | HDAC4 (0.39) | — | |
| SCHEMBL25094706 | 0.64 | HDAC4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |