Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520386 | 0.76 | RXRA (0.34) | SLC6A4SLC6A3SLC6A2CASP1 | |
| SCHEMBL8417707 | 0.69 | ALOX15 (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10726449 | 0.68 | SLC6A4 (0.48) | SLC6A4SLC6A3SLC6A2CYP2D6CNR1 | |
| SCHEMBL7722936 | 0.68 | RXRA (0.67) | — | |
| SCHEMBL1124803 | 0.67 | MAOA (0.56) | SLC6A4SLC6A3SLC6A2CYP2D6CNR1 | |
| SCHEMBL24021289 | 0.67 | SLC6A4 (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1566412 | 0.66 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL1832696 | 0.64 | SLC6A3 (0.36) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL5085593 | 0.64 | SLC6A4 (0.72) | SLC6A4SLC6A3SLC6A2CYP2D6 | |
| SCHEMBL8419298 | 0.64 | RXRA (0.47) | SLC6A4SLC6A3SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |