Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591779 | 0.92 | GAA (0.43) | GAAHTTALDH1A1LMNAMEN1 | |
| SCHEMBL28268057 | 0.91 | GAA (0.66) | GAAHTTSMN1; SMN2ALDH1A1DUSP3 | |
| SCHEMBL7589132 | 0.88 | GAA (0.54) | GAAHTTSMN1; SMN2ALDH1A1DUSP3 | |
| SCHEMBL8416686 | 0.86 | MAPT (0.43) | GAAHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10620309 | 0.82 | ALDH1A1 (0.50) | GAAHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6865356 | 0.82 | GAA (0.51) | GAAHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8417926 | 0.80 | GAA (0.46) | GAAHTTSMN1; SMN2ALDH1A1DUSP3 | |
| SCHEMBL7594424 | 0.78 | GAA (0.46) | GAAHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11267996 | 0.78 | GAA (0.52) | GAAHTTSMN1; SMN2ALDH1A1DUSP3 | |
| SCHEMBL8374395 | 0.78 | GAA (0.48) | GAAHTTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |