Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591779 | 0.94 | GAA (0.43) | MAPTALDH1A1NPC1GAAATM | |
| SCHEMBL7590944 | 0.89 | KDM4E (0.43) | ALDH1A1SMN1; SMN2NPC1GAALMNA | |
| SCHEMBL8418099 | 0.86 | GAA (0.56) | MAPTALDH1A1SMN1; SMN2GAAATM | |
| SCHEMBL8415185 | 0.84 | GAA (0.41) | MAPTALDH1A1SMN1; SMN2NPC1GAA | |
| SCHEMBL6865356 | 0.84 | GAA (0.51) | MAPTALDH1A1SMN1; SMN2GAAATM | |
| SCHEMBL10620309 | 0.84 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2GAAATM | |
| SCHEMBL11341597 | 0.80 | CYP3A4 (0.55) | MAPTALDH1A1SMN1; SMN2GAAATM | |
| SCHEMBL8374395 | 0.80 | GAA (0.48) | MAPTALDH1A1SMN1; SMN2GAAATM | |
| SCHEMBL8380052 | 0.80 | KDM4E (0.44) | ALDH1A1SMN1; SMN2NPC1GAALMNA | |
| SCHEMBL905517 | 0.79 | KDM4E (0.48) | ALDH1A1SMN1; SMN2NPC1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782564-B1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1999-09-01 | — | — | EP | disclosed |