Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | HRH2 | P25021 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 4/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417734 | 0.99 | CHRNA7 (0.38) | CHRNA7SIGMAR1HRH3HRH2HRH1 | |
| SCHEMBL8421598 | 0.83 | LTA4H (0.42) | CHRNA7HRH3 | |
| Hydrochloric Acid SCHEMBL8420397 | 0.81 | LTA4H (0.42) | CHRNA7HRH3 | |
| SCHEMBL8420501 | 0.70 | MEN1 (0.39) | CHRNA7HRH3KCNH2 | |
| SCHEMBL8968385 | 0.68 | MMP13 (0.39) | — | |
| SCHEMBL1542065 | 0.66 | MEN1 (0.47) | HRH3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8969873 | 0.66 | MMP13 (0.40) | — | |
| SCHEMBL6572089 | 0.65 | MEN1 (0.45) | HRH3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1542586 | 0.65 | GAA (0.47) | HRH3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11761259 | 0.65 | GAA (0.56) | HRH3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |