Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 15/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968385 | 0.99 | MMP13 (0.39) | MMP13FDFT1MMP2 | |
| SCHEMBL27458909 | 0.96 | MMP13 (0.38) | MMP13FDFT1MMP2 | |
| SCHEMBL8417820 | 0.86 | FDFT1 (0.37) | MMP13FDFT1MMP2 | |
| Hydrochloric Acid SCHEMBL8418615 | 0.86 | FDFT1 (0.37) | MMP13FDFT1MMP2 | |
| Hydrochloric Acid SCHEMBL8772629 | 0.83 | SIGMAR1 (0.43) | MMP13 | |
| SCHEMBL8772717 | 0.83 | SIGMAR1 (0.43) | MMP13 | |
| SCHEMBL8969019 | 0.82 | LTA4H (0.42) | MMP13FDFT1MMP2 | |
| Hydrochloric Acid SCHEMBL8968667 | 0.82 | LTA4H (0.42) | MMP13FDFT1MMP2 | |
| SCHEMBL8707627 | 0.76 | HRH3 (0.42) | — | |
| SCHEMBL8772617 | 0.76 | ALDH1A1 (0.46) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |