Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18743799 | 0.80 | KDM4E (0.33) | HTR2AHRH1TDP1CYP3A4PGR | |
| SCHEMBL4346261 | 0.79 | FDPS (0.34) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL8416724 | 0.78 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4HTR2A | |
| SCHEMBL3401455 | 0.75 | KMT2A (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4HTR2A | |
| SCHEMBL10285142 | 0.75 | TSHR (0.35) | CHRM1ADRA1ADRD3TSHRADRA2A | |
| SCHEMBL1612949 | 0.75 | TSHR (0.35) | CHRM1ADRA1ADRD3TSHRADRA2A | |
| SCHEMBL18519247 | 0.74 | CA2 (0.35) | CHRNB2CHRNB4CHRNA4CA1CA2 | |
| SCHEMBL18084197 | 0.69 | FDPS (0.38) | CA2FDPS | |
| SCHEMBL19889381 | 0.69 | FDPS (0.34) | TSHRFDPS | |
| SCHEMBL15314795 | 0.68 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714885-B1 | Preparation process of aminoacetamide derivative | EISAI CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0714885-A2 | Preparation process of aminoacetamide derivative | EISAI CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |