SCHEMBL8418962

SCHEMBL8418962

CNc1ccc(S(=O)(=O)c2ccc(NC)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.67
CA2 P00918 2/20 0.67
CA1 P00915 1/20 0.67
ALDH1A1 P00352 6/20 0.54
CYP3A4 P08684 3/20 0.54
RECQL P46063 2/20 0.54
HSD17B10 Q99714 2/20 0.54
TP53 P04637 1/20 0.54
THRB P10828 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
CASP1 P29466 1/20 0.54
HIF1A Q16665 1/20 0.54
MAPT P10636 3/20 0.54
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
CA9 Q16790 1/20 0.53
GAA P10253 2/20 0.52
ATM Q13315 1/20 0.50
PKM P14618 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19681874 0.91 GAA (0.70) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL6976640 0.91 HTR6 (0.61) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL9806707 0.89 HTR6 (0.67) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL18270518 0.89 ALDH1A1 (0.55) CA12CA2CA1ALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL28149921 0.87 CA2 (0.53) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL9806735 0.85 ALDH1A1 (0.61) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL11699237 0.85 CA12 (0.52) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL20038664 0.84 CA12 (0.50) CA12CA2CA1ALDH1A1CYP3A4
SCHEMBL19392261 0.84 PKM (0.74) CA12CA2CA1ALDH1A1MAPT
SCHEMBL4471540 0.84 ALDH1A1 (0.78) CA12CA2CA1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
US-5071947-A Polymerization of a bismaleimide and an aromatic secondary diamine in the presence of dicumyl peroxide and imidazole mixed catalyst LUCKY, LTD. (KR) 1991-12-10 US claimed
US-4996279-A Crosslinked epoxies from diepoxides, diphenols, primary and secondary amines with stiff and flexible units; melt processability SHELL OIL COMPANY (US) 1991-02-26 US claimed
US-11174371-B2 Graphene-augmented composite materials THE BOEING COMPANY (US) 2021-11-16 US disclosed
US-10875986-B2 Graphene fiber for aerospace composites THE BOEING COMPANY (US) 2020-12-29 US disclosed
US-10851215-B2 Graphene-augmented composite materials THE BOEING COMPANY (US) 2020-12-01 US disclosed
US-20190338087-A1 GRAPHENE-AUGMENTED COMPOSITE MATERIALS THE BOEING COMPANY (US) 2019-11-07 US disclosed
US-10400075-B2 Graphene-augmented composite materials THE BOEING COMPANY (US) 2019-09-03 US disclosed
EP-3040307-B1 GRAPHENE FIBER FOR AEROSPACE COMPOSITES BOEING CO (US) 2019-07-31 EP disclosed
US-20190203017-A1 GRAPHENE-AUGMENTED COMPOSITE MATERIALS THE BOEING COMPANY (US) 2019-07-04 US disclosed
US-4960912-A EPOXY RESINS, POLYEPOXDIES SHELL OIL COMPANY (US) 1990-10-02 US disclosed
US-4940809-A Bis-anthrols and bis-naphthols and diglycidyl ethers thereof SHELL OIL COMPANY (US) 1990-07-10 US disclosed
US-4908424-A Bis-anthrols and bis-naphthols and diglycidyl ethers thereof SHELL OIL COMPANY (US) 1990-03-13 US disclosed
US-4861810-A DIEPOXIDES, MODULUS, TOUGHNESS, GLASS TRANSITION TEMPERATURE SHELL OIL COMPANY (US) 1989-08-29 US disclosed
US-4847011-A USED FOR POLYETHER THERMOPLASTIC RESIN COMPOSITIONS SHELL OIL COMPANY (US) 1989-07-11 US disclosed
EP-0249263-A2 Thermoplastic polymer composition having thermosetting processing characteristics SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-12-16 EP disclosed
US-4140658-A Cyanamides of secondary amines as epoxy curing agents CIBA-GEIGY CORPORATION (US) 1979-02-20 US disclosed
US-4041208-A ENERGY ABSORBERS, LAMINATED GLASS SHEETS USEFUL AS AUTOMOBILE WINDSHIELDS PPG INDUSTRIES, INC. (US) 1977-08-09 US disclosed