Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | RXRG | P48443 | 2/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.56 |
| ▸ | RARG | P13631 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012498 | 0.76 | RXRA (0.63) | RXRARXRGRARARARBRARG | |
| SCHEMBL8419298 | 0.73 | RXRA (0.47) | RXRARXRGRARARARBRARG | |
| SCHEMBL7731726 | 0.73 | RXRA (1.00) | RXRARXRGRARARARBRARG | |
| SCHEMBL7731728 | 0.73 | RXRA (1.00) | RXRARXRGRARARARBRARG | |
| SCHEMBL8419189 | 0.71 | RXRA (0.67) | RXRARXRGRARARARBRARG | |
| SCHEMBL19207570 | 0.67 | MAOA (0.54) | — | |
| SCHEMBL8520386 | 0.67 | RXRA (0.34) | RXRARXRGRARARARBRARG | |
| SCHEMBL9248524 | 0.66 | GABRA1 (0.42) | RXRARXRGGABRA1GABRB2HMGCR | |
| SCHEMBL27871630 | 0.66 | GABRA1 (0.38) | RXRARXRGGABRA1GABRB2HMGCR | |
| SCHEMBL7996385 | 0.65 | RXRA (0.59) | RXRARXRGRARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |