Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417764 | 0.86 | HPGD (0.34) | — | |
| SCHEMBL8419750 | 0.85 | SMN1; SMN2 (0.34) | MRGPRX1 | |
| SCHEMBL8969934 | 0.70 | MMP13 (0.46) | — | |
| SCHEMBL8520797 | 0.70 | FFAR1 (0.38) | — | |
| SCHEMBL27408212 | 0.68 | TSHR (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8919982 | 0.66 | MMP13 (0.46) | — | |
| SCHEMBL8420487 | 0.65 | TSHR (0.31) | — | |
| SCHEMBL8419827 | 0.65 | CYP2D6 (0.31) | MRGPRX1 | |
| SCHEMBL8919905 | 0.63 | FDFT1 (0.41) | — | |
| SCHEMBL8442126 | 0.63 | TDP1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |