Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419832 | 0.81 | GABRA1 (0.31) | MRGPRX1 | |
| SCHEMBL8419750 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2TSHRMRGPRX1 | |
| SCHEMBL8421878 | 0.71 | CHRNA7 (0.36) | CHRNA7SCN1ASCN2ASCN3A | |
| SCHEMBL8419827 | 0.68 | CYP2D6 (0.31) | MAPTMRGPRX1CYP3A4 | |
| SCHEMBL8970015 | 0.67 | MMP13 (0.52) | — | |
| SCHEMBL733385 | 0.67 | HSD17B10 (0.59) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL4357259 | 0.66 | HSD17B10 (0.58) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL1255394 | 0.66 | HSD17B10 (0.58) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL8923497 | 0.64 | CNR1 (0.32) | HPGDALOX15KDM4EALDH1A1KMT2A | |
| SCHEMBL29437924 | 0.64 | HSD17B10 (0.76) | HSD17B10HPGDALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |