Biphenyl

Biphenyl

SCHEMBL8419917

NC(=O)NONC(N)=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 1/20 0.45
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
BCAT2 O15382 1/20 0.43
ALDH1A1 P00352 1/20 0.43
DHODH Q02127 1/20 0.42
IKBKB O14920 1/20 0.42
MAPT P10636 3/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL11033740 0.80 TSHR (0.53) MEN1KMT2ALMNANPC1RAB9A
Biphenyl SCHEMBL9421865 0.80 LMNA (0.48) LMNANPC1RAB9ACTDSP1BCAT2
Biphenyl SCHEMBL335359 0.79 ALDH1A1 (0.60) LMNAKDM4EBCAT2ALDH1A1DHODH
Biphenyl SCHEMBL473288 0.79 ALDH1A1 (0.60) LMNAKDM4EBCAT2ALDH1A1DHODH
Biphenyl SCHEMBL4593266 0.79 ALDH1A1 (0.60) LMNAKDM4EBCAT2ALDH1A1DHODH
Biphenyl SCHEMBL1952613 0.79 ALDH1A1 (0.60) LMNAKDM4EBCAT2ALDH1A1DHODH
SCHEMBL28199563 0.78 MGLL (0.47) LMNANPC1RAB9ACTDSP1BCAT2
Biphenyl SCHEMBL3276083 0.78 TSHR (0.50) MEN1KMT2ALMNAKDM4ENPC1
SCHEMBL4910502 0.77 MAPT (0.48) MEN1KMT2ANPC1RAB9AALDH1A1
Biphenyl SCHEMBL8014588 0.77 ALDH1A1 (0.63) KMT2ALMNAKDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939753-A1 ARYL BENZOYL UREA DERIVATIVE AND PESTICIDAL COMPOSITION COMPRISING THE SAME Dongbu Hannong Chemical Co., Ltd. (KR) 1999-09-08 EP disclosed
WO-1997024321-A1 ARYL BENZOYL UREA DERIVATIVE AND PESTICIDAL COMPOSITION COMPRISING THE SAME HANWHA CORPORATION (KR) 1997-07-10 WO disclosed