Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.37 |
| ▸ | FEN1 | P39748 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421041 | 0.88 | F10 (0.38) | F10SQORSCN9APTGES2P2RX3 | |
| SCHEMBL8419446 | 0.86 | ALOX5AP (0.40) | F10PTGS2SQORALOX5APFEN1 | |
| SCHEMBL8419971 | 0.85 | PTGS2 (0.48) | PTGS2SQOR | |
| SCHEMBL8419780 | 0.77 | DHODH (0.41) | F10PTGS2SQORPTGES2 | |
| SCHEMBL8421107 | 0.76 | PTGS2 (0.47) | F10PTGS2SQORALOX5APFEN1 | |
| SCHEMBL8419782 | 0.73 | PTGS2 (0.47) | F10PTGS2ALOX5APFEN1 | |
| SCHEMBL8421043 | 0.73 | CA2 (0.43) | PTGS2 | |
| SCHEMBL8419905 | 0.71 | PTGS2 (0.40) | F10PTGS2ALOX5APFEN1 | |
| SCHEMBL8419449 | 0.70 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL8092684 | 0.70 | PTGS2 (0.49) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |