Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422575 | 0.89 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL8420658 | 0.88 | SMN1; SMN2 (0.52) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL8418953 | 0.86 | ALDH1A1 (0.60) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL8768524 | 0.85 | ALDH1A1 (0.59) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8420219 | 0.83 | SMN1; SMN2 (0.58) | ALDH1A1GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8420661 | 0.78 | HTT (0.55) | SMN1; SMN2HTTPLK1POLBHPGD | |
| SCHEMBL8422577 | 0.77 | HTT (0.54) | KDM4EGAASMN1; SMN2HTTPOLB | |
| SCHEMBL8422576 | 0.74 | AKR1C2 (0.48) | KDM4EALDH1A1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8420285 | 0.72 | SMN1; SMN2 (0.62) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8422566 | 0.72 | NR1H4 (0.59) | SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |