Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418974 | 0.84 | F2 (0.31) | — | |
| SCHEMBL8422341 | 0.75 | MAPT (0.33) | GAAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL8418937 | 0.69 | — | — | |
| SCHEMBL8420177 | 0.68 | HSD17B10 (0.38) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7555716 | 0.61 | CYP1A2 (0.43) | GAAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7824393 | 0.58 | MAPT (0.46) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7410059 | 0.58 | CYP2D6 (0.39) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8422340 | 0.57 | MEN1 (0.35) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL4991673 | 0.57 | SMN1; SMN2 (0.73) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23279842 | 0.53 | F2 (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866573-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |