Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420334 | 0.84 | TGFBR1 (0.32) | — | |
| SCHEMBL8418912 | 0.80 | HTT (0.31) | F2PRSS1PIK3CD | |
| SCHEMBL8418937 | 0.71 | — | — | |
| SCHEMBL8422341 | 0.63 | MAPT (0.33) | — | |
| SCHEMBL8422340 | 0.60 | MEN1 (0.35) | F2PRSS1 | |
| SCHEMBL7819433 | 0.58 | F2 (0.62) | F2PRSS1PIK3CD | |
| SCHEMBL23279842 | 0.54 | F2 (0.53) | F2PRSS1 | |
| SCHEMBL7819612 | 0.54 | F2 (0.51) | F2PRSS1 | |
| SCHEMBL45843 | 0.54 | RECQL (0.70) | — | |
| SCHEMBL14960629 | 0.53 | SOST (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866573-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |