Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420334 | 0.75 | TGFBR1 (0.32) | MAPTGAACHRM4NPC1RAB9A | |
| SCHEMBL8418937 | 0.68 | — | — | |
| SCHEMBL8418974 | 0.63 | F2 (0.31) | — | |
| SCHEMBL8420177 | 0.62 | HSD17B10 (0.38) | MAPTHTTTSHRSMN1; SMN2GAA | |
| SCHEMBL7555716 | 0.62 | CYP1A2 (0.43) | MAPTHTTTSHRSMN1; SMN2GAA | |
| SCHEMBL7824393 | 0.60 | MAPT (0.46) | MAPTHTTTSHRNPC1RAB9A | |
| SCHEMBL7410059 | 0.60 | CYP2D6 (0.39) | MAPTHTTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL7817035 | 0.58 | F2 (0.47) | MAPTHTTTSHRMEN1KMT2A | |
| SCHEMBL4991673 | 0.57 | SMN1; SMN2 (0.73) | SMN1; SMN2GAANPC1RAB9AMEN1 | |
| SCHEMBL23279842 | 0.53 | F2 (0.53) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866573-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |