Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767951 | 0.92 | HTT (0.53) | POLBHTTSMN1; SMN2NR1H4HPGD | |
| SCHEMBL8768533 | 0.86 | ALDH1A1 (0.51) | POLBHTTSMN1; SMN2HPGDLTB4R | |
| SCHEMBL8422577 | 0.85 | HTT (0.54) | POLBHTTSMN1; SMN2NR1H4LTB4R | |
| SCHEMBL8418610 | 0.85 | HTT (0.51) | POLBHTTSMN1; SMN2NR1H4HPGD | |
| SCHEMBL8767987 | 0.83 | HTT (0.49) | POLBHTTSMN1; SMN2NR1H4HPGD | |
| SCHEMBL8422541 | 0.83 | POLB (0.48) | POLBHTTSMN1; SMN2NR1H4HPGD | |
| SCHEMBL8767163 | 0.82 | HTT (0.47) | POLBHTTSMN1; SMN2NR1H4LTB4R | |
| SCHEMBL8767170 | 0.82 | HTT (0.47) | POLBHTTSMN1; SMN2NR1H4LTB4R | |
| SCHEMBL8422415 | 0.82 | HPGD (0.48) | POLBSMN1; SMN2HPGDFFAR1MEN1 | |
| SCHEMBL8422466 | 0.81 | PTGES (0.50) | POLBHTTSMN1; SMN2NR1H4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | claimed |
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |