Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422577 | 0.91 | HTT (0.54) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8767951 | 0.87 | HTT (0.53) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8768544 | 0.86 | ALDH1A1 (0.50) | SMN1; SMN2POLBHCAR2HPGD | |
| SCHEMBL8767170 | 0.85 | HTT (0.47) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8767163 | 0.85 | HTT (0.47) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8418610 | 0.84 | HTT (0.51) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8420643 | 0.83 | POLB (0.51) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8420292 | 0.79 | GAA (0.68) | HTTSMN1; SMN2FFAR1POLBNR1H4 | |
| SCHEMBL8418917 | 0.77 | POLB (0.47) | HTTSMN1; SMN2POLBNR1H4LTB4R | |
| SCHEMBL8420661 | 0.77 | HTT (0.55) | HTTSMN1; SMN2FFAR1POLBNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |