Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420643 | 0.92 | POLB (0.51) | HTTSMN1; SMN2POLBFFAR1NR1H4 | |
| SCHEMBL8767987 | 0.87 | HTT (0.49) | HTTSMN1; SMN2POLBFFAR1NR1H4 | |
| SCHEMBL8422577 | 0.85 | HTT (0.54) | HTTSMN1; SMN2POLBFFAR1NR1H4 | |
| SCHEMBL8767163 | 0.85 | HTT (0.47) | HTTSMN1; SMN2POLBFFAR1NR1H4 | |
| SCHEMBL8418610 | 0.85 | HTT (0.51) | HTTSMN1; SMN2POLBFFAR1NR1H4 | |
| SCHEMBL8767170 | 0.83 | HTT (0.47) | HTTSMN1; SMN2POLBFFAR1NR1H4 | |
| SCHEMBL8422541 | 0.83 | POLB (0.48) | HTTSMN1; SMN2POLBNR1H4HPGD | |
| SCHEMBL8768533 | 0.82 | ALDH1A1 (0.51) | HTTSMN1; SMN2POLBHPGDMEN1 | |
| SCHEMBL8422466 | 0.81 | PTGES (0.50) | HTTSMN1; SMN2POLBNR1H4HPGD | |
| SCHEMBL8420292 | 0.80 | GAA (0.68) | HTTSMN1; SMN2POLBFFAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |