Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420178 | 0.94 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDMAPTPTGS2 | |
| SCHEMBL8421979 | 0.94 | ALDH1A1 (0.42) | ALDH1A1GAAHPGDMAPTPTGS2 | |
| SCHEMBL8422371 | 0.87 | MAPT (0.45) | ALDH1A1CYP2C9MMP2NPY5RMMP1 | |
| SCHEMBL8420749 | 0.86 | MAPT (0.52) | ALDH1A1HPGDCYP2C9NPY5RMAPT | |
| SCHEMBL8420791 | 0.85 | GAA (0.43) | ALDH1A1GAAHPGDMAPTPTGS2 | |
| SCHEMBL8420831 | 0.85 | GAA (0.43) | ALDH1A1GAAHPGDPTGS2SMN1; SMN2 | |
| SCHEMBL8641068 | 0.85 | PTGS2 (0.53) | ALDH1A1GAAHPGDCYP2C9PTGS2 | |
| SCHEMBL8636817 | 0.84 | PTGS2 (0.42) | ALDH1A1GAAHPGDMMP2MMP1 | |
| SCHEMBL8689203 | 0.84 | MMP2 (0.39) | ALDH1A1GAAHPGDMMP2MMP1 | |
| SCHEMBL8422134 | 0.84 | MAPT (0.51) | ALDH1A1GAACYP2C9MMP2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |