Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134461 | 0.87 | ALDH1A1 (0.41) | BCL2A1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL11159138 | 0.85 | L3MBTL1 (0.47) | BCL2A1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9133587 | 0.83 | ALDH1A1 (0.47) | BCL2A1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5967266 | 0.81 | MLYCD (0.48) | ALDH1A1SMN1; SMN2GAAKMT2AMEN1 | |
| SCHEMBL8426236 | 0.81 | KDM4E (0.41) | BCL2A1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL29173926 | 0.79 | ALDH1A1 (0.45) | BCL2A1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9152678 | 0.77 | HTR3E (0.48) | ALDH1A1HTTRAB9ASMN1; SMN2AOC3 | |
| Hydrochloric Acid SCHEMBL8378174 | 0.77 | MAPT (0.48) | BCL2A1ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7496040 | 0.75 | HTR3E (0.58) | ALDH1A1HTTRAB9ASMN1; SMN2MAPT | |
| SCHEMBL13603840 | 0.75 | MAPT (0.44) | BCL2A1ALDH1A1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919785-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-07-06 | — | — | US | disclosed |