⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528318 | 0.82 | — | — | |
| SCHEMBL9308379 | 0.82 | — | — | |
| SCHEMBL8422450 | 0.80 | — | — | |
| SCHEMBL4941379 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL3475630 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL9170187 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL29281761 | 0.77 | — | — | |
| SCHEMBL961093 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL2303044 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL523852 | 0.76 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487291-B1 | Photocurable silicon composition, and method of making same | LOCTITE CORP (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5348986-A | Polysiloxanes capped with mixture of curable groups, gels, acrylated polymers | LOCTITE CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| US-5182315-A | Endcapping | LOCTITE CORPORATION (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0487291-A2 | Photocurable silicon composition, and method of making same | LOCTITE CORPORATION (US) | 1992-05-27 | — | — | EP | disclosed |