Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18219809 | 0.91 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL11324715 | 0.90 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL523852 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL2303044 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL2409855 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL8422452 | 0.78 | — | — | |
| SCHEMBL2528318 | 0.78 | — | — | |
| SCHEMBL332509 | 0.77 | TSHR (0.47) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8422450 | 0.76 | — | — | |
| SCHEMBL3475630 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000993-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO INC (US) | 2023-01-05 | — | — | US | disclosed |
| US-11291731-B2 | Silicon based drug conjugates and methods of using same | BLINKBIO, INC. (US) | 2022-04-05 | — | — | US | disclosed |
| US-9931407-B2 | Silicon based drug conjugates and methods of using same | BLINKBIO, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-9809677-B2 | Polycarbonate composition and article comprising the same | LG CHEM, LTD. (KR) | 2017-11-07 | — | — | US | disclosed |
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
| WO-2016183359-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. (US) | 2016-11-17 | — | — | WO | disclosed |
| US-20160326321-A1 | POLYCARBONATE COMPOSITION AND ARTICLE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2016-11-10 | — | — | US | disclosed |
| US-7851524-B2 | Antistatic agents, compositions thereof, and methods of manufacture | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-7569714-B2 | Antistatic and antidust agents, compositions thereof, and methods of manufacture | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-08-04 | — | — | US | disclosed |
| US-20090184442-A1 | ANTISTATIC AGENTS, COMPOSITIONS THEREOF, AND METHODS OF MANUFACTURE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-23 | — | — | US | disclosed |
| US-20080075981-A1 | Magnetic recording medium | HITACHI MAXELL, LTD. (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-0700951-B1 | Polyorganosiloxane and process for producing the same | SHOWA DENKO KK (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0700951-A1 | Polyorganosiloxane and process for producing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5491203-A | COMPRISES POLYSILSESQUIOXANE STRUCTURE; HAS METHYL GROUP AND A REACTIVE GROUP ON SIDE CHAINS; SUITABLE AS POLYMER MODIFIER; CROSSLINKING; COATINGS | SHOWA DENKO K. K. (JP) | 1996-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | ALDH1A1 2151/4885LMNA 3473/4885HSD17B10 3435/4885 |
| US-11291731-B2 | Silicon based drug conjugates and methods of using same | CD44, MSN, AS3MT | ALDH1A1 2151/4885LMNA 3473/4885HSD17B10 3435/4885 |
| US-20230000993-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | ALDH1A1 2151/4885LMNA 3473/4885HSD17B10 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.