Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422407 | 0.84 | ALDH1A1 (0.63) | ALDH1A1NR1H4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8422576 | 0.81 | AKR1C2 (0.48) | PLK1ALDH1A1AKR1C2AKR1C1NR1H4 | |
| SCHEMBL8768524 | 0.77 | ALDH1A1 (0.59) | PLK1ALDH1A1AKR1C2AKR1C1NR1H4 | |
| SCHEMBL8420661 | 0.74 | HTT (0.55) | PLK1NR1H4RAB9ASMN1; SMN2POLB | |
| SCHEMBL8418953 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8419001 | 0.72 | KDM4E (0.57) | PLK1ALDH1A1AKR1C2AKR1C1MEN1 | |
| SCHEMBL8422577 | 0.71 | HTT (0.54) | AKR1C2AKR1C1NR1H4SMN1; SMN2POLB | |
| SCHEMBL8422575 | 0.70 | SMN1; SMN2 (0.50) | PLK1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8420658 | 0.69 | SMN1; SMN2 (0.52) | PLK1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8767682 | 0.69 | LMNA (0.59) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |