Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775743 | 0.86 | — | — | |
| SCHEMBL16579863 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL518099 | 0.72 | POLB (0.33) | POLB | |
| SCHEMBL24235798 | 0.69 | — | — | |
| SCHEMBL13438266 | 0.69 | — | — | |
| SCHEMBL19880109 | 0.69 | POLB (0.32) | POLB | |
| SCHEMBL2503457 | 0.69 | — | — | |
| SCHEMBL1100489 | 0.69 | LMNA (0.35) | POLB | |
| SCHEMBL7817961 | 0.69 | — | — | |
| SCHEMBL26832461 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| US-20230286903-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2023-09-14 | — | — | US | disclosed |
| US-20170088545-A1 | CARBOXAMIDE INHIBITORS | NOVARTIS AG (CH) | 2017-03-30 | — | — | US | disclosed |
| CN-1050599-C | Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines | ROHM & HAAS (US) | 2000-03-22 | — | — | CN | disclosed |
| EP-0638545-B1 | Process for preparing 1,2-diacyl-2-t-alkylhydrazides | ROHM & HAAS (US) | 1999-10-13 | — | — | EP | disclosed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | disclosed |
| CN-1109049-A | Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines | ROHM & HAAS (US) | 1995-09-27 | — | — | CN | disclosed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0638545-A1 | Process for preparing 1,2-diacyl-2-t-alkylhydrazides | ROHM AND HAAS COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286903-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | PLTP, LNPK, PLIN3 | POLB 1805/4885 |
| US-20170088545-A1 | CARBOXAMIDE INHIBITORS | SMURF1, SMURF2, SMYD2 | POLB 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.