SCHEMBL8683402

SCHEMBL8683402

CCCCCC(Cl)(CC(Cl)(Cl)Cl)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.38
SMPD1 P17405 2/20 0.37
CES2 O00748 1/20 0.37
AKR1B1 P15121 1/20 0.37
PPARG P37231 6/20 0.35
PPARD Q03181 6/20 0.35
PPARA Q07869 6/20 0.35
GPR84 Q9NQS5 5/20 0.35
HDAC11 Q96DB2 5/20 0.35
TSHR P16473 4/20 0.35
ALDH1A1 P00352 2/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35
PTPN1 P18031 2/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
MEN1 O00255 1/20 0.35
ESR1 P03372 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8422908 0.85 SMPD1 (0.45) FDPSSMPD1CES2PPARGPPARD
SCHEMBL4154139 0.82 SMPD1 (0.42) FDPSSMPD1CES2PPARGPPARD
SCHEMBL29200163 0.82 SMPD1 (0.42) FDPSSMPD1CES2PPARGPPARD
SCHEMBL9243044 0.77 FDPS (0.39) FDPSAKR1B1PPARGPPARDPPARA
SCHEMBL9425842 0.74 FDPS (0.38) FDPSSMPD1CES2
SCHEMBL6052974 0.74 FDPS (0.48) FDPSSMPD1AKR1B1
SCHEMBL2207815 0.74 FDPS (0.43) FDPSSMPD1CES2AKR1B1PPARG
SCHEMBL6003007 0.74 FDPS (0.43) FDPSSMPD1CES2AKR1B1PPARG
SCHEMBL3284980 0.72 SMPD1 (0.45) FDPSSMPD1CES2PPARGPPARD
SCHEMBL658156 0.72 SMPD1 (0.45) FDPSSMPD1CES2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5786504-A HALOGENATED UNSATURATED ESTERS; USEFUL IN ETHYLENE POLYMERIZATION PROCESSES UNIROYAL CHEMICAL COMPANY, INC. (US) 1998-07-28 US disclosed